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Atrioventriclar septal defects (AVSD) is an important congenital heart disease (CHD) with variable clinical
and echocardiographic forms.
Materials and Methods: All patients with this diagnosis seen at the Sudan Heart Centre between July 2004
and December 2008 were included in the study. Patients were evaluated clinically, by electrocardiograms and
echocardiography and followed up.
Results: One hundred and thirty two patients with AVSD were identified out of 2480 patients with CHD.
Patients were divided into 4 groups: Group 1: complete AVSD , group 2: partial AVSD,group 3 complex AVSD
and group 4: AVSD without primum ASD. Group 1 included 57patients, Down’s syndrome was present in 56%
of patients and the mean age at presentation was 30 months. Twelve patients had surgery with no mortality.
Twenty nine percent of patients in this group had Eisenmenger’s syndrome on presentation. Group 2 included
32 patients, Down’s syndrome was present in 29% of patients and the mean age at presentation was79 months.
Eleven patients had complete surgical repair with one mortality. Group 3 included 41 patients with AVSD
associated with major anomalies. Twenty nine percent had surgical palliation with one mortality while 43%
were found to be inoperable. Group 4 included 2 patients with Downs>s syndrome and a large ventricular
Conclusion: The frequency of AVSD in the Sudan was comparable to the literature. Corrective and palliative
surgery is available but patients need to be diagnosed and referred early before they develop Eisenmenger>s
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